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WHAT ARE SOME POTENTIAL RISKS ASSOCIATED WITH INVESTING IN CRYPTOCURRENCIES

Cryptocurrencies like Bitcoin are highly speculative investments and come with greater risks than traditional investments like stocks, bonds, and real estate. Some of the major risks include:

Volatility Risk: The valuation of cryptocurrencies is not tied to any economic indicators and is only determined by market demand which tends to be highly volatile. This makes the value of holdings in crypto vulnerable to large swings on any given day or hour. Between 2017 and 2018, the total market capitalization of all cryptocurrencies fell from $830 billion to just $120 billion, a drop of over 85%. Such volatility means the value of holdings can crash significantly in a very short period.

Liquidity Risk: Compared to traditional assets, cryptocurrency markets lack liquidity. This means that during times of high volatility or low demand, it may be difficult to sell cryptocurrency holdings at reasonable prices. Low liquidity combined with high volatility can result in amplification of losses during downturns as sellers flood the markets looking to exit positions.

Bubble Risk: There is a persistent debate around whether the huge increases in cryptocurrency prices, particularly during 2017, represented an unsustainable bubble. Given the high speculation in the asset class and lack of economic fundamentals tied to valuation, there is a risk that cryptocurrency mania could repeat itself and result in another crash that wipes out significant value.

Fraud and Hack Risk: Cryptocurrency exchanges and wallets, which are needed to buy, sell and hold cryptocurrency, have been frequent targets of hacks and theft. Millions of dollars in digital currencies have been stolen by hacking exchanges and exploiting technical loopholes. There have also been instances of exchanges and Initial Coin Offering (ICO) projects turning out to be fraudulent. Such operational and security risks translate to potential losses of holdings for investors.

Regulatory Risk: As global financial regulators are still assessing how to classify cryptocurrencies and what regulatory framework to apply, there is uncertainty around evolving rules. Tighter regulations could limit participation and ease of conversion between crypto and fiat currencies. Contradictory regulatory stances across countries could also undermine the fungibility of digital assets. Changes in rules can impact value and market viability of certain cryptocurrencies.

Acceptance Risk: For cryptocurrencies to be adopted as a long term store of value and medium of exchange, they need to gain significant merchant and consumer acceptance. Their usage for “real economy” transactions remains limited. If major corporations, merchants, and governments show lack of interest in accepting crypto payments over time, it brings into question the long term usability and valuation proposition of these digital assets.

Technology Risk: The algorithms, protocols and software governing cryptocurrencies have not been stress tested over long periods by large scale mainstream usage. Potential bugs, security holes or technical limitations that are discovered in the future could undermine confidence in networks and result in forks or other problems affecting value of holdings.

Tax Risk: Tax laws governing profits or losses from buying and selling cryptocurrencies continue to evolve in most jurisdictions. Depending on individual country rules and the investor’s local tax laws, any gains realized from crypto investments could be treated differently than traditional assets for tax purposes, which creates uncertainty. Tax compliance on crypto transactions also poses challenges for individuals and regulators.

Competing Crypto Risk: The cryptocurrency space remains innovative, with new digital currency projects emerging regularly that aim to improve upon earlier blockchains or offer different value propositions. Older cryptocurrencies run the risk of losing market share to newer entrants over time if they fail to develop or scale sufficiently. Investments in any single crypto hold the risk of superior technology making that particular asset obsolete or less competitive.

Lack of Intrinsic Value: Unlike stocks which hold claims on real assets of publicly traded companies, or fiats which are backstopped by governments, cryptocurrencies have no intrinsic value of their own. Their worth depends entirely on self-fulfilling speculative demand without tangible assets or cash flows backing them up. This abstraction makes cryptos vulnerable if market sentiment shifts drastically away from them.

Cryptocurrencies represent highly speculative and volatile investments that carry unique and significant risks compared to traditional assets. Their long-term acceptance and viability remains uncertain due to technological, regulatory and competitive challenges. All these factors make cryptos risky proportionate bets that could result in complete loss of capital for investors. Only active traders with solid risk management and investors with strong risk tolerance should consider crypto exposure as part of a well-diversified portfolio.

WHAT ARE SOME COMMON CHALLENGES ORGANIZATIONS FACE WHEN IMPLEMENTING PREDICTIVE ANALYTICS

Data issues: One of the biggest hurdles is obtaining high-quality, relevant data for building accurate predictive models. Real-world data is rarely clean and can be incomplete, inconsistent, duplicated, or contain errors. Premises must first invest time and resources into cleaning, harmonizing, and preparing their raw data before it can be useful for analytics. This data wrangling process is often underestimated.

Another data challenge is lack of historical data. For many types of predictive problems, models require large volumes of historical data covering many past examples to learn patterns and generalize well to new data. Organizations may not have accumulated sufficient data over time for all the variables and outcomes they want to predict. This limits what types of questions and predictions are feasible.

Technical skills: Building predictive models and deploying analytics programs requires specialized technical skills that many organizations do not have in-house, such as data scientists, predictive modelers, data engineers, and people with expertise in machine learning techniques. It can be difficult for groups to build these competencies internally and there is high demand/short supply of analytics talent, which drives up costs of outside hiring. Lack of required technical skills is a major roadblock.

Model interpretation: Even when predictive models are successfully developed, determining how to interpret and explain their results can be challenging. Machine learning algorithms can sometimes produce “black box” models whose detailed inner workings are difficult for non-experts to understand. For many applications it is important to convey not just predictions but also the factors and rationales behind them. More transparent, interpretable models are preferable but can be harder to develop.

Scaling issues: Creating predictive models is usually just the first step – the bigger challenge is operationalizing analytics by integrating models into core business processes and systems on an ongoing, industrial scale over time. Scaling the use of predictive insights across large, complex organizations faces hurdles such as model governance, workflow redesign, data integration problems, and ensuring responsible, equitable use of analytics for decision-making. The operational challenges of widespread deployment are frequently underestimated.

Institutional inertia: Even when predictions could create clear business value, organizational and political barriers can still impede adoption of predictive analytics. Teams may lack incentives to change established practices or take on new initiatives requiring them to adopt new technical skills. Silos between business and technical groups can impede collaboration. Also, concerns about privacy, fairness, bias, and the ethics of algorithmic decisions slowing progress. Overcoming institutional reluctance to change is a long-term cultural challenge.

Business understanding: Building predictive models requires close collaboration between analytics specialists and subject matter experts within the target business domain. Translating practical business problems into well-defined predictive modeling problems is challenging. The analytics team needs deep contextual knowledge to understand what specific business questions can and should be addressed, which variables are useful as predictors, and how predictions will actually be consumed and used. Lack of strong business understanding limits potential value and usefulness.

Evaluation issues: It is difficult to accurately evaluate the true financial or business impact of predictive models, especially for problems where testing against real future outcomes must wait months or years. Without clear metrics and evaluation methodologies, it is challenging to determine whether predictive programs are successful, cost-effective, and delivering meaningful returns. Lack of outcome tracking and ROI measurement hampers longer-term prioritization and investment in predictive initiatives over time.

Privacy and fairness: With the growth of concerns over privacy, algorithmic bias, and fairness, organizations must ensure predictive systems are designed and governed responsibly. Satisfying regulatory, technical, and social expectations regarding privacy, transparency, fairness is a complex challenge that analytics teams are only beginning to address and will take sustained effort over many years. Navigating these societal issues complicates predictive programs.

Budget and priorities: Establishing predictive analytics programs requires substantial upfront investment and ongoing resource commitment over many years. Competing budget priorities, lack of executive sponsorship, and short-term thinking can limit sustainable funding and priority for long-term strategic initiatives like predictive analytics. Without dedicated budget and management support, programs stagnate and fail to achieve full potential value.

Overcoming these common challenges requires careful planning, cross-functional collaboration, technical skills, governance, ongoing resources, and long-term organizational commitment. Those able to successfully address data, technical, operational, cultural and societal barriers lay the foundation for predictive success, while others risk programs that underdeliver or fail to achieve meaningful impact. With experience, solutions are emerging but challenges will remain substantial for the foreseeable future.

WHAT ARE SOME EXAMPLES OF RARE PEDIATRIC CANCERS THAT COULD BE THE FOCUS OF A CAPSTONE PROJECT

Rare cancers that affect children are of particular interest for capstone projects because they often receive less research funding and attention compared to more common adult cancers. Developing a deeper understanding of the molecular mechanisms, treatments, and patients’ experiences with rare pediatric cancers can help advance care for these vulnerable populations. Here are some examples of rare pediatric cancers that would be suitable topics for an in-depth senior or graduate-level capstone project:

Neuroblastoma is a rare cancer that forms in certain types of nerve tissue and most commonly appears in young children, often presenting in the adrenal glands, chest, abdomen or neck. It accounts for around 15% of all childhood cancers but less than 1% of all cancers diagnosed. Despite being rare, neuroblastoma is responsible for more deaths among children with solid tumors than any other cancer. A capstone project could explore new targeted therapies and immunotherapies in development for high-risk neuroblastoma. The student could conduct a literature review of recent clinical trials and analyze molecular markers to identify patient subgroups most likely to respond to certain treatments. Understanding the genetics and biology of neuroblastoma in more detail could help accelerate the development of personalized, precision medicine approaches.

Ewing sarcoma is the second most common bone cancer in children after osteosarcoma. It remains quite rare, accounting for less than 1% of all cancers and 3% of childhood cancers. Ewing sarcoma most often appears in bones of the pelvis, legs, chest, or spine and is characterized by translocations linking the EWS gene to an ETS family gene. A capstone project on Ewing sarcoma could comprehensively review past and current standard of care therapies, while also evaluating promising new targeted drugs and immunotherapies in preclinical and early phase clinical testing. Interviews with patients, families and clinicians could provide insights into the challenges of living with and treating this aggressive bone cancer. Identifying biomarkers for early detection and response to treatment is another important area warranting further research highlighted by such a project.

Rhabdomyosarcoma is a type of soft tissue sarcoma that develops from skeletal muscle cells or muscles in other parts of the body. It represents about 3-4% of all childhood cancers but is still considered rare. The most common locations are the head and neck region, genitourinary tract, and extremities. Subtypes include embryonal, alveolar and pleomorphic. A capstone project could focus specifically on the more aggressive alveolar subtype, analyzing its distinctive genetic mutations and exploring combination therapies to overcome resistance. The student might profile a series of alveolar rhabdomyosarcoma cases at their institution to identify clinical or molecular characteristics associated with improved outcomes. Interviews with long-term survivors could offer unique perspectives on the emotional and physical impacts as well as care needs over time.

Atypical teratoid/rhabdoid tumor (AT/RT) is an extremely rare and highly malignant type of cancerous brain tumor that primarily affects young children. It develops from cells in the central nervous system and has a very poor prognosis despite intensive multimodal therapy. AT/RT represents less than 1% of all pediatric central nervous system tumors but is the focus of considerable research efforts given its lethal nature. A project delving into the molecular hallmarks and epigenetic dysregulation characteristic of AT/RT could survey targeted agents in preclinical testing and early stage clinical trials. Collaboration with neuro-oncologists may provide access to tumor samples for exploring biomarkers of sensitivity and resistance. Investigating supportive care interventions and quality of life for patients undergoing complex treatment regimens could also yield important insights.

Wilms tumor, also known as nephroblastoma, begins in the kidneys and is the most common malignant tumor of the kidneys in children. It represents approximately 6% of all childhood cancers yet remains defined as a rare cancer. Wilms tumor is usually found in children younger than 5 years old, with 80-90% of cases arising before the age of 6. A capstone topic could extensively review protocols from cooperative clinical trials groups to analyze factors influencing event-free survival overtime. The student might conduct interviews with nursing professionals and child life specialists to gain perspective on psychosocial support needs throughout the patient journey. Exploration of genomic characterization efforts aimed at more precisely stratifying risk could also yield valuable insights for precision oncology approaches.

Rare pediatric cancers like neuroblastoma, Ewing sarcoma, rhabdomyosarcoma, AT/RT and Wilms tumor present opportunities for in-depth capstone study. Delving into disease biology, therapeutic developments, clinical research challenges, and patient/family experiences could advance understanding and care for these underserved populations. With a comprehensive literature review augmented by primary data collection, a student could produce an original research project meaningfully contributing to progress against devastating pediatric cancers.

WHAT WERE SOME OF THE CHALLENGES FACED DURING THE IMPLEMENTATION OF THE FOOD WASTE REDUCTION STRATEGY

One of the major challenges faced during the implementation of food waste reduction strategies was changing public behavior and mindsets around food. For many years, most people have viewed excess food as unimportant and not given much thought to wasting it. Things like clearing one’s plate, over-ordering at restaurants, or throwing out old leftovers and expired foods were ingrained habits. Shifting such habitual behaviors requires a significant mindset change, which can be difficult to achieve. It requires sustained education campaigns to raise awareness of the issue and its impacts, as well as motivation for people to adjust their daily food-related routines and habits.

Another behavioral challenge is that reducing food waste often requires more planning and coordination within households. Things like meticulously planning out meals, sticking to grocery lists, adjusting portion sizes, and making better use of leftovers necessitates more effort and time compared to past habits. While improving skills like meal planning, it is an adjustment that not everyone finds easy to make. For families with both parents working long hours, seeking convenience is also an understandable priority, leaving little time or energy for meticulous waste-reduction efforts.

From a business and operations perspective, one challenge is the lack of reliable data on food waste amounts. Most organizations, whether food manufacturers, grocery retailers or food service companies, have historically not tracked the scale of food that gets wasted within their facilities and supply chains. Without robust baseline data, it is difficult to analyze root causes, identify priorities and set meaningful targets for improvement. Some have also been hesitant to publicly share waste data for risk of reputational damage. The lack of common measurement standards has made industry-wide benchmarking and goal setting a challenge.

On the policy front, the mixed competencies shared between different levels and departments of government have made coordinated action difficult. Food waste touches on the responsibilities of agriculture, environment, waste collection, business regulations, public awareness campaigns and more. There is sometimes lack of clarity on who should take the lead, and duplication or gaps can occur between different actors. The complexity with multiple stakeholders across many domains further impedes swift, aligned policy progress to drive systemic changes.

Even when strategies are set, enforcement is a big challenge especially related to food date labeling policies. Standardizing and simplifying date labels to distinguish between ‘Best Before’ – indicating quality rather than safety – and ‘Use By’ date is an important intervention. Inconsistent application of new labeling rules by some in the vast food industry has undermined the effectiveness of this policy change to reduce consumer confusion and subsequent waste. Stronger compliance mechanisms are needed.

From a technological standpoint, while innovative solutions are emerging, scaling these up to have meaningful impact requires extensive investments of time and capital. Food redistribution through apps needs to overcome challenges like adequate coverage, logistical issues in arranging pick ups, necessity of refrigerated transportation, and standardizing quality parameters of donor and recipient organizations. Similarly, food waste valorization is still at a nascent, experimental phase with challenges of developing financially viable business models at commercial scale. These solutions are also capital intensive to set up advanced processing facilities.

Even simple measures like home composting have faced adoption challenges due to requirements like space, installation efforts, maintenance skills and concerns over pests and smells. Compostable packaging is not universally available and green bins for food scrap collection are not scaled up widely in all geographies to make participation easy. Expanded waste collection infrastructure requires substantial capital allocations by local governments already facing budget constraints.

From a supply chain coordination perspective, a key challenge is data and technology integration across the long and complex path food takes from farms to processing units to transport networks to retailers to finally consumers. Lack of end-to-end visibility impedes root cause analysis of where and why waste is originating. It also restricts opportunities for collaborative optimization of inventory, ordering and demand planning practices to minimize food left unconsumed at any stage. Silos between different entities and lack of incentives for open data sharing have hampered integrated solutions.

Reducing food waste faces behavioral, operational, policy-related, technological, financial as well as supply chain coordination challenges. It requires multifaceted, long-term efforts spanning awareness drives, standardized measurement, supportive regulations, scaled infrastructure, collaborative innovation and adaptability to local conditions. The complexity of root causes necessitates system-wide cooperation between industry, governments, researchers and communities to achieve meaningful impact over time. While progress has been made, continued dedication of resources and coordination between different stakeholders remains important to sustain momentum in tackling this massive global issue.

WHAT ARE SOME RESOURCES OR TOOLS THAT CAN HELP ME DEVELOP A WEB OR MOBILE APPLICATION FOR A CAPSTONE PROJECT

Coding Languages and Frameworks:

HTML/CSS – These core web technologies are essential for building any type of web application. HTML defines the content and structure, while CSS controls the design and layout. Many sites are built with just these languages.

JavaScript – As the core scripting language of the web, JavaScript is necessary for adding dynamic and interactive elements to web pages and applications. It is supported across all major browsers. Advanced JavaScript frameworks can be used to build complex single-page apps.

Python – A versatile programming language used widely in industry. Python can be used to build both front-end web apps using frameworks like Django and Flask, as well as back-end APIs and microservices. Python is also well-suited for data analysis, machine learning, and scripting tasks.

Java – The most popular language for traditional back-end web application development. The Spring framework is commonly used for creating enterprise-level Java web apps. Java can also be used to build Android mobile apps.

Swift/Objective-C – Required for building native iOS mobile apps running on iPhone and iPad. Swift is the primary language nowadays, replacing Objective-C, but it’s good to be familiar with both.

Kotlin – The preferred language for Android application development alongside Java. Kotlin code works directly with Android SDK and is fully interoperable with Java.

React – A JavaScript library for building complex user interfaces and single-page apps. React makes it easier to create interactive UIs and is commonly paired with frameworks like Redux. Widely used by Facebook, Instagram, and other big companies.

Angular – Another popular JavaScript framework, developed by Google. Similar capabilities to React but with a more fully-featured framework approach.

Node.js – A JavaScript runtime built on Chrome’s V8 JavaScript engine. Node.js lets you write backend apps in JavaScript and is commonly used for REST API development alongside frameworks like Express.

Flutter – Google’s open-source mobile app SDK for building high-quality native applications for iOS and Android from a single codebase with the Dart programming language.

Development Environments:

Visual Studio Code – A free, lightweight but powerful source code editor made by Microsoft for Windows, Linux and macOS. Highly customizable and extensible.

Android Studio – The official IDE for developing Android apps.Provides an integrated environment for building Android apps with tools for compiling, debugging, and performance optimization.

Xcode – The official IDE for developing iOS apps on Mac systems. All development and deployment of apps is handled within Xcode.

PyCharm – A Python IDE developed by JetBrains, optimized for writing, debugging, and profiling Python code. Great for Django and Flask web development.

IntelliJ IDEA – A Java IDE that can also be used for Android, Python, JavaScript, etc. Very powerful but heavier than alternatives.

Databases:

MySQL – The world’s most popular open-source relational database. Wide support and easy to use with many web frameworks.

Postgres – Another powerful open-source relational database used heavily in industry. Considered more robust than MySQL for complex requirements.

MongoDB – The dominant document-oriented NoSQL database. Flexible for unstructured data and frequently used with Node, Python and mobile backends.

Firebase – Google’s mobile platform with a realtime database well suited for mobile app development. Handles authentication, hosting, push notifications and more.

Testing & Deployment:

Jest – JavaScript testing framework primarily used with React apps. Easy to setup and runs fast with straightforward API.

JUnit – De facto unit testing standard for Java apps. Integrates cleanly with frameworks like Spring Boot.

Postman – Useful GUI tool for sending HTTP requests to test and document RESTful APIs during development.

Travis CI/GitHub Actions – Popular continuous integration services that can automate building/testing code and deploying releases when changes are pushed to GitHub.

Heroku – Leading cloud application platform. Makes it simple to deploy and host web/mobile backends written in most languages including Java, Python, Node, Ruby etc. Provides automated deploys from GitHub.

AWS – Industry-leading cloud provider offering comprehensive PaaS and IaaS services to deploy production apps at scale. Services like EC2, S3, API Gateway, Lambda,etc. More complex but powerful capabilities over Heroku.

Android Play Store/iOS App Store – Final deployment destinations for distributing production mobile apps to end users. Requires setting up signed release builds with their respective app stores.

With the vast selection of languages, frameworks, environments and tools listed above, students have everything they need available for free or at low cost to design, develop, test and ship a professional quality capstone project for the web or mobile. Carefully selecting the right stack based on the project requirements and one’s skills/interests will ensure success in completing an impactful application.